肝净一生--乙肝|乙肝携带者|愿景|hbv|hbver

这几篇文章都是诺贝尔获得者FIRE等的作品,介绍RNA干扰的技术与最新的进展..

包括:

1.RNA Interference:Ready For A Close-up?

2.Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

3.Revealing the world of RNA interference

4.RNA Interference and mRNA Silencing, 2004: How Far Will They Reach?

5.Small molecules in an RNAi world

6.Nucleic acid structure and intracellular immunity: some recent ideas from the world of RNAi(摘要)

RNAi(RNA interference)即RNA干扰,是指通过反义RNA 与正链RNA形成双链RNA特异性地抑制靶基因的转录后表达的现象,它通过人为地引入与内源靶基因具有相同序列的双链RNA(有义RNA 和反义RNA)，从而诱导内源靶基因的mRNA降解,达到阻止基因表达的目的.